Welcome to episode 469 of The Whole View! This week, Stacy and Dr. Sarah examine insulin sensitivity vs. lifestyle to see how diet, exercise, stress, and sleep can play a factor. If you enjoy the show, please review it on iTunes! The Whole View, Episode 469: Insulin Sensitivity vs. Lifestyle Welcome back to episode 469! (0:28) Not long ago in Episode 467, Stacy and Dr. Sarah talked about how moderate sugar can fit into a healthy diet. One aspect of that conversation not fully explored was how lifestyle factors influence insulin sensitivity and regulation. Blood sugar is tangential to many of the topics Dr. Sarah and Stacy talk about on this show. Why Care About Insulin? The body produces insulin inside beta cells in the islet of Langerhans in the pancreas and stores Insulin in insulin granules until serum glucose levels increase. (8:40) Our blood sugar increases when we consume carbohydrates. That rise in glucose stimulates insulin release by the pancreatic β-cell through ATP-sensitive K+ channel (KATPchannel)-dependent and -independent signaling pathways (1–3). The insulin then facilitates the transport of glucose into the body’s cells (via GLUT4) and signals to the liver to convert glucose into glycogen and triglycerides for storage. Chronically elevated […]
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